Effect of cabergoline on parkinsonian tremor assessed by long-term actigraphy

S Binder, G Deuschl, J Volkmann - European neurology, 2009 - karger.com
Background: Tremor is one of the cardinal symptoms in Parkinson's disease, but only few
clinical studies have focussed on its therapy as the primary endpoint. One reason is the
substantial fluctuation of tremor severity over time, which is difficult to capture and may
render momentary clinical assessments unreliable. Methods: We evaluated the usefulness
of a novel wrist-worn actigraph allowing long-term recordings of tremor in a pilot study, in
which we assessed the therapeutic effect of cabergoline on tremor in 10 patients with tremor …
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